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Minarovits, Janos (Herausgeber); Niller, Hans Helmut (Herausgeber):
Patho-Epigenetics of Disease - encadernado, livro de bolso2012, ISBN: 1461433444
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2012
ISBN: 1461433444
[EAN: 9781461433446], Neubuch, [PU: Springer New York 2012-05-23, New York], Language: ENG, Books
no/na Biblio.co.uk
2012, ISBN: 9781461433446
Springer, 2012-05-23. 2012. Hardcover. Good., Springer, 2012-05-23, 2.5
Dados bibliográficos do melhor livro correspondente
| Autor: | |
| Título: | |
| Número ISBN: |
Dados detalhados do livro - Patho-Epigenetics of Disease
EAN (ISBN-13): 9781461433446
ISBN (ISBN-10): 1461433444
Livro de capa dura
Ano de publicação: 2012
Editor/Editora: Springer-Verlag GmbH
465 Páginas
Peso: 0,852 kg
Língua: Englisch
Livro na base de dados desde 2007-07-24T01:05:42+01:00 (Lisbon)
Página de detalhes modificada pela última vez em 2022-04-27T21:44:26+01:00 (Lisbon)
Número ISBN/EAN: 1461433444
Número ISBN - Ortografia alternativa:
1-4614-3344-4, 978-1-4614-3344-6
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: minar, helmut, nill, niller
Título do livro: ostberlin, epigenetics and disease
Dados da editora
Autor: Janos Minarovits; Hans Helmut Niller
Título: Patho-Epigenetics of Disease
Editora: Springer; Springer US
466 Páginas
Ano de publicação: 2012-05-23
New York; NY; US
Impresso / Feito em
Peso: 0,881 kg
Língua: Inglês
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
POD
XIV, 466 p.
BB; Medical Microbiology; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Mikrobiologie und Virologie; Verstehen; infectious diseases; Medicine/Public Health, general; Virology; Infectious Diseases; Immunology; Medical Microbiology; Health Sciences; Virology; Diseases; Immunology; Medizin, allgemein; Mikrobiologie (nicht-medizinisch); Krankheiten und Störungen; Immunologie; BC; EA
In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry identical or nearly identical DNA sequences.
Because DNA methyltransferase I (DNMT1) associates with replication foci during S phase and prefers hemimethylated DNA as a substrate, DNMT1 ensures the clonal propagation of cytosine methylation patterns (maintenance methylation). Thus, DNA methylation may provide a memory function by helping progeny cells to “remember” their proper cellular identity.
modification of histone tails.
epigenetic alterations malignant tumors epigenetic dysregulation a wide spectrum of human diseases epigenetic memory via Epigenetic regulatory mechanisms.- Role of DNMT3B Mutations in the Pathogenesis of ICF Syndrome.- Dysfunction of the Methyl-Cpg Binding Protein Mecp2 in Rett Syndrome.- Epigenetic Alterations in Glioblastoma Multiforme.- Aberrant Epigenetic Regulation in Breast Cancer.- The Impact of Epigenetic Alterations on Diagnosis, Prediction and Therapy of Prostate Cancer.- Epigenetic Reprogramming in Lung Carcinomas.- Epigenetic changes in virus associated neoplasms.- Genetic and Epigenetic Determinants of Aggression.- Co-Regulation and Epigenetic Dysregulation in Schizophrenia and Bipolar Disorder.- Disruption of Epigenetic Mechanisms in Autoimmune Syndromes.- Imprinting Disorders.- Epigenetics of cardiovascular diseases.- Microbe-induced epigenetic alterations.In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry identical or nearly identical DNA sequences.
Because DNA methyltransferase I (DNMT1) associates with replication foci during S phase and prefers hemimethylated DNA as a substrate, DNMT1 ensures the clonal propagation of cytosine methylation patterns (maintenance methylation). Thus, DNA methylation may provide a memory function by helping progeny cells to “remember” their proper cellular identity.
modification of histone tails.
epigenetic alterations malignant tumors epigenetic dysregulation a wide spectrum of human diseases epigenetic memory viaPatho-Epigenetics is a new discipline, and it’s covered here in detail
Written by experts in this exciting new field
Brings together recent results of epigenetic research with special attention to disease development
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