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2010, ISBN: 3527326030
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Rautio, Jarkko (EDT):
Prodrugs and Targeted Delivery : Towards Better ADME Properties - encadernado, livro de bolso2011, ISBN: 3527326030
[EAN: 9783527326037], Gebraucht, wie neu, [PU: Wiley-VCH], Unread book in perfect condition., Books
2011
ISBN: 3527326030
[EAN: 9783527326037], Gebraucht, wie neu, [PU: Wiley-VCH], Unread book in perfect condition., Books
2011, ISBN: 3527326030
[EAN: 9783527326037], Neubuch, [PU: Wiley-VCH], Books
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ISBN: 9783527326037
John Wiley & Sons . Hardback. New. pp. 520, John Wiley & Sons, 6
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Dados detalhados do livro - Prodrugs and Targeted Delivery: Towards Better ADME Properties (Methods and Principles in Medicinal Chemistry, 47, Band 47)
EAN (ISBN-13): 9783527326037
ISBN (ISBN-10): 3527326030
Livro de capa dura
Ano de publicação: 2010
Editor/Editora: Rautio, Jarkko, Wiley-VCH
496 Páginas
Peso: 1,104 kg
Língua: eng/Englisch
Livro na base de dados desde 2007-01-16T11:28:29+00:00 (Lisbon)
Página de detalhes modificada pela última vez em 2023-09-23T09:37:34+01:00 (Lisbon)
Número ISBN/EAN: 3527326030
Número ISBN - Ortografia alternativa:
3-527-32603-0, 978-3-527-32603-7
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: kubinyi, rauti, raimund, hugo, wiley vch, gerd folkers
Título do livro: delivery beyond, principles chemistry
Dados da editora
Autor: Jarkko Rautio
Título: Methods and Principles in Medicinal Chemistry; Prodrugs and Targeted Delivery - Towards Better ADME Properties
Editora: Wiley-VCH; Wiley-VCH
496 Páginas
Ano de publicação: 2010-12-15
Impresso / Feito em
Peso: 1,432 kg
Língua: Inglês
185,00 € (DE)
190,20 € (AT)
Available
170mm x 240mm x 39mm
BB; Hardcover, Softcover / Chemie; Medizinische Chemie, Pharmazeutische Chemie; Verstehen; Medizin, Gesundheit; Arzneimittelentwicklung; Arzneimittelforschung; Chemie; Chemistry; Drug Discovery & Development; Drug Formulation & Delivery; Toxicology; Toxikologie; Wirkstoff; Wirkstoffformulierung, Wirkstofftransport; Wirkstoffforschung u. -entwicklung; Wirkstoffforschung u. -entwicklung; Wirkstoffformulierung, Wirkstofftransport; Toxikologie
By definition, drugs are highly active substances that are beneficial if they act at the right time and in the right place, but can cause harm otherwise. A clever strategy to ensure that a drug only becomes active when needed is to "camouflage" it. Such camouflaged, i.e. deactivated, drugs that become chemically or biochemically activated once they reach their site of action are called prodrugs. This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies, beginning at the early stages of the development process, while also discussing organ- and site-selective prodrugs. From the contents: * Prodrug design and intellectual property * Prodrugs addressing ADMET issues * Codrugs and soft drugs * Preclinical and clinical consideration for prodrugs This book is a valuable reference for all companies employing medicinal chemists by giving a practice-oriented overview of a key strategy in modern drug discovery and development.Outros livros adicionais, que poderiam ser muito similares com este livro:
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9783527633173 Prodrugs and Targeted Delivery (Jarkko Rautio)
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