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Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate | A. Israel (u. a.) | Buch | Research and Perspectives in Alzheimer's Disease | HC runder Rücken kaschiert | Englisch | 2002 - Israel, A.
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Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate | A. Israel (u. a.) | Buch | Research and Perspectives in Alzheimer's Disease | HC runder Rücken kaschiert | Englisch | 2002 - encadernado, livro de bolso

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Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate / A. Israel (u. a.) / Buch / Research and Perspectives in Alzheimer's Disease / HC runder Rücken kaschiert / Englisch / 2002 - Israel, A.
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Israel, A.:

Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate / A. Israel (u. a.) / Buch / Research and Perspectives in Alzheimer's Disease / HC runder Rücken kaschiert / Englisch / 2002 - encadernado, livro de bolso

2002, ISBN: 9783540430735

[ED: Gebunden], [PU: Springer Berlin], Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegen… mais…

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Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate A. Israel (u. a.) Buch Research and Perspectives in Alzheimer's Disease HC runder Rücken kaschiert Englisch 2002 - Israel, A.
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Israel, A.:
Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate A. Israel (u. a.) Buch Research and Perspectives in Alzheimer's Disease HC runder Rücken kaschiert Englisch 2002 - encadernado, livro de bolso

2002

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Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate
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ISBN: 9783540430735

Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders? Brain development an… mais…

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Israel, Alain, de Strooper, Bart, Checler, Frederic:
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Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate
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Número ISBN:

3540430733


Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders? Brain development and function require complex cellular and molecular processes controlled by a number of different signaling mechanisms. One such signaling mechanism, the Notch pathway, has been recognized as an important player in the regulation of cellfate decisions during early neural development. However, the action of this evolutionary conserved and widely used cell-cell interaction mechanism is not confined to the developing nervous system. In addition, recent studies have shown that elucidating the mechanism of Notch signaling and its role in the brain is important for our understanding of neurological disorders such as Alzheimer's disease and cerebral arteriopathy CADASIL.

Dados detalhados do livro - Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate


EAN (ISBN-13): 9783540430735
ISBN (ISBN-10): 3540430733
Livro de capa dura
Ano de publicação: 2002
Editor/Editora: Springer
180 Páginas
Peso: 0,471 kg
Língua: eng/Englisch

Livro na base de dados desde 2007-05-30T12:16:33+01:00 (Lisbon)
Página de detalhes modificada pela última vez em 2023-08-25T20:28:16+01:00 (Lisbon)
Número ISBN/EAN: 3540430733

Número ISBN - Ortografia alternativa:
3-540-43073-3, 978-3-540-43073-5
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: frédéric, alain, bart, christen, stroop, lee israel
Título do livro: fate, keeping, neurodegeneration, alzheimer disease, israei

Dados da editora

Autor: A. Israel; B. de Strooper; F. Checler; Y. Christen
Título: Research and Perspectives in Alzheimer's Disease; Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate
Editora: Springer; Springer Berlin
158 Páginas
Ano de publicação: 2002-05-28
Berlin; Heidelberg; DE
Língua: Inglês
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
Available
XVI, 158 p.

BB; Hardcover, Softcover / Medizin/Klinische Fächer; Neurologie und klinische Neurophysiologie; Verstehen; ALzheimer's Disease; Nervous System; Proteolysis; neurons; nicastrin; presenilin; ubiquitin-proteasome pathway; Neurology; Neuroscience; Neurowissenschaften; BC

Regulated Intramembrane Proteolysis — New Lessons from Lipid Metabolism and the Unfolded Protein Response.- Notch Signaling in the Brain: More than Just a Developmental Story.- Control of Notch Activity by the Ubiquitin-Proteasome Pathway.- A Presenilin-Dependent S3-Like ?-Secretase Cleavage of the ?-Amyloid Precursor Protein.- New Non-Peptidic Inhibitors of ?-Secretase Abolish A? Production Without Modifying Notch Cleavage.- Presenilins, APP, and Notch: Proteolysis from Womb to Tomb.- Missorting of the Dendritic Cell Adhesion Molecule Telencephalin in Presenilin-Deficient Neurons.- ?APP Processing, its Biology and Alzheimer’s Disease.- Further Analysis of the Nicastrin: Presenilin Complex.- PS1 Interacts With and Facilitates ?-Catenin Turnover.- ?-Catenin, Presenilin, and the Synaptic-Adherens Junction Complex.- Vascular Smooth Muscle Cells Are the Primary Target of the Events Leading from Notch3 Mutations to CADASIL.

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