[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is the most common type of neoplasia in… mais…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. 80 pp. Englisch, Books<
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[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing Mrz 2011], This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. 80 pp. Englisch, Books<
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[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN KLINISCHE FÄCHER VIRAL VECTOR GENE THERAPY BREAST CANCER, Dieser Artikel ist ein Print on Demand Artikel und … mais…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN KLINISCHE FÄCHER VIRAL VECTOR GENE THERAPY BREAST CANCER, Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vannucci LauraLaura Vannucci graduated in Biology in 2004 and received the Ph.D in Experimental and Molecular Oncology in 2009. Her Researches on gene therapy and vaccination were carried out with Prof. Mauro Pistello at Retrovirus ., Books<
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[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is the most common type of neoplasia in… mais…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. 80 pp. Englisch, Books<
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[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing Mrz 2011], This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer is the most common type o… mais…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing Mrz 2011], This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer. 80 pp. Englisch, Books<
NEW BOOK. Custos de envio: EUR 9.90 BuchWeltWeit Inh. Ludwig Meier e.K., Bergisch Gladbach, Germany [57449362] [Rating: 5 (von 5)]
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN KLINISCHE FÄCHER VIRAL VECTOR GENE THERAPY BREAST CANCER, Dieser Artikel ist ein Print on Demand Artikel und … mais…
[EAN: 9783844322071], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN KLINISCHE FÄCHER VIRAL VECTOR GENE THERAPY BREAST CANCER, Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vannucci LauraLaura Vannucci graduated in Biology in 2004 and received the Ph.D in Experimental and Molecular Oncology in 2009. Her Researches on gene therapy and vaccination were carried out with Prof. Mauro Pistello at Retrovirus ., Books<
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Softcover, PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from the UK., [PU: LAP Lambert Academic Publishing]<
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Breast cancer is the most common type of neoplasia in women. Most of hereditary cases are associated with mutations of breast cancer-associated genes (BRCA). Preventive mastectomy and chemoprevention are the only approaches available so far to prevent the development of neoplasia in patients with specific genetic background. However, side effects and invasiveness of these procedures make necessary the development of alternative strategies. This book describes a novel approach to prevent breast cancer based on the restoration of BRCA1 functional gene into target cells using an engineered virus. In fact viruses have developed an efficient mechanism to deliver their genetic material into target cells; virus-derived vectors take advantages of this ability to vehiculate transgenes cells. To this aim a lentiviral vector expressing BRCA1 gene was produced. Restoration of gene function was validated in tumor and primary cells derived from patient encoding an inactive form of BRCA1, that, following gene delivery, restored the ability to repair DNA damages upon exposition to ionizing radiations These results pave the way to develop novel preventative approaches against human breast cancer.
Dados detalhados do livro - Gene therapy for breast cancer treatment: Engineered viruses: to turn the bad into the good
EAN (ISBN-13): 9783844322071 ISBN (ISBN-10): 3844322078 Livro de capa dura Livro de bolso Ano de publicação: 2011 Editor/Editora: LAP LAMBERT Academic Publishing
Livro na base de dados desde 2007-09-26T20:46:40+01:00 (Lisbon) Página de detalhes modificada pela última vez em 2023-10-08T08:53:12+01:00 (Lisbon) Número ISBN/EAN: 3844322078
Número ISBN - Ortografia alternativa: 3-8443-2207-8, 978-3-8443-2207-1 Ortografia alternativa e termos de pesquisa relacionados: Autor do livro: vannucci Título do livro: the treatment, therapy, cancer, the gene