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Kinetics of Drug Action - J. M. Van Rossum
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Kinetics of Drug Action - Livro de bolso

2012, ISBN: 364266539X

[EAN: 9783642665394], Neubuch, [PU: Springer Berlin Heidelberg], PHARMAKOLOGIE; PHARMACOLOGY; RESEARCH, Druck auf Anfrage Neuware -Most drugs, toxins, hormones, and the like bring about t… mais…

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ISBN: 9783642665394

Most drugs, toxins, hormones, and the like bring about their biologic actions by reacting with specific receptors somewhere in the body. Scientists working in all areas of biologic scienc… mais…

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Rossum, J.M. van:
Kinetics of Drug Action - primeira edição

2012

ISBN: 9783642665394

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Rossum, J. M. Van (Herausgeber):
Kinetics of Drug Action - Livro de bolso

2012, ISBN: 364266539X

Softcover reprint of the original 1st ed. 1977 Kartoniert / Broschiert Medizin, allgemein, Pharmakologie; Pharmacology; research, mit Schutzumschlag 11, [PU:Springer Berlin Heidelberg; … mais…

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J.M. van Rossum:
Kinetics of Drug Action - primeira edição

2012, ISBN: 9783642665394

Livro de bolso

Buch, Softcover, Softcover reprint of the original 1st ed. 1977, [PU: Springer Berlin], Springer Berlin, 2012

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Dados detalhados do livro - Kinetics of Drug Action J.M. van Rossum Editor


EAN (ISBN-13): 9783642665394
ISBN (ISBN-10): 364266539X
Livro de bolso
Ano de publicação: 2012
Editor/Editora: Springer Berlin Heidelberg Core >1 >T

Livro na base de dados desde 2012-09-20T15:08:43+01:00 (Lisbon)
Página de detalhes modificada pela última vez em 2023-10-30T21:28:46+00:00 (Lisbon)
Número ISBN/EAN: 9783642665394

Número ISBN - Ortografia alternativa:
3-642-66539-X, 978-3-642-66539-4
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: von rossum, van rossum
Título do livro: kinetics drug action


Dados da editora

Autor: J.M. van Rossum
Título: Handbook of Experimental Pharmacology; Kinetics of Drug Action
Editora: Springer; Springer Berlin
438 Páginas
Ano de publicação: 2012-01-09
Berlin; Heidelberg; DE
Impresso / Feito em
Língua: Inglês
106,99 € (DE)
109,99 € (AT)
118,00 CHF (CH)
POD
XVIII, 438 p.

BC; Hardcover, Softcover / Medizin/Allgemeines; Medizin, allgemein; Verstehen; Pharmakologie; drug; kinetics; pharmacology; research; Health Sciences; Pharmacy; Pharmazie, Apotheke; BB

General Introduction.- 1 Physicochemical Fundamentals and Thermodynamics of the Membrane Transport of Drugs..- I. Introduction.- II. Systems and Membrane Types.- III. Classification of Membrane Transport.- IV. Kinetics and Thermodynamics of Membrane Transport.- Appendix. Glossary of Symbols.- References.- 2 Pharmacokinetics. Kinetic Aspects of Absorption, Distribution, and Elimination of Drugs..- I. Introduction.- II. Pharmacokinetic Models.- III. Models for Single-Dose Administration.- IV. Multiple Dose Administration.- V. Conclusion.- References.- 3 Pharmacokinetics of Biotransformation..- I. Introduction.- II. Conclusion.- References.- 4 General Theory of Drug-Receptor Interactions. Drug-Receptor Interaction Models. Calculation of Drug Parameters..- I. Introduction.- II. Drugs, Receptors and Effects.- III. Agonistic Interaction.- IV. Competitive Interaction.- V. Metactoid Interaction.- VI. Metaffinoid Interaction.- VII. Functional Interaction.- VIII. Plural Affinities.- IX. Numerical Expressions of Intrinsic Activity and Affinity.- References.- 5 A Critical Survey of Receptor Theories of Drug Action..- I. Introduction.- II. The Mathematics of Drug-Receptor Interactions.- III. Occupation Theories of Drug Action.- IV. The Rate Theory of Drug Action.- V. A General Discussion of the Various Receptor Models.- VI. A General Discussion of the Possible Uses of Receptor Models.- Appendix. Glossary of Symbols.- References.- 6 Drug-Receptor Inactivation: A New Kinetic Model..- I. Introduction.- II. Energetics of Receptor Activity.- III. Models in Which Trigger Energy is Generated.- IV. Models Involving Irreversible Alterations of Agonist or Receptor.- V. A Receptor Inactivation Theory.- VI. Stationary State Behavior with Single Agonists.- VII. Transient State Behavior with Single Agonists.- VIII. Stationary State Behavior with Agonist-Antagonist Mixtures.- IX. Transient State Behavior with Agonist-Antagonist Mixtures.- X. General Discussion.- XI. Summary.- Addendum A.- Addendum B.- Appendices: Glossary—Generalized Rate Equations for the Receptor Inactivation Model—“On” Effect—“Off” Effect—Analysis of Oscillations—Receptor Interactions with Agonist-Antagonist Mixtures.- References.- 7 Kinetics of Drug-Receptor Interaction..- I. Introduction.- II. Diffusion of Drug to Receptor.- III. Intermolecular Forces in Drug-Receptor Reactions.- IV. Kinetics of Drug-Receptor Association and Dissociation.- V. Possibilities for Measuring Rate Constants in Drug-Receptor Interaction.- VI. Conformational Changes in the Drug-Receptor Complex.- VII. Kinetics of Drug-Receptor Interaction, Including Conformational Changes.- VIII. Some Other Notions in Molecular Pharmacology.- IX. Activation Parameters.- References.- Conclusion.- Author Index.

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