ISBN: 9783847331704

The hypothesis was gap junction communication also plays a role in coordinating transcript rhythms of the circadian-regulated genes in chicken retina. To test this hypothesis, a chicken e… mais…

The hypothesis was gap junction communication also plays a role in coordinating transcript rhythms of the circadian-regulated genes in chicken retina. To test this hypothesis, a chicken embryonic retinal explant culture was established. The robust, self-sustaining, and light-entrainable iodopsin and Arylalkylamine N-acetyltransferase (AANAT) mRNA rhythms were observed under different lighting conditions. This observation supports use of the explant cultures to test effects of gap junction blockers on gene expression rhythms in retina. The two reversible gap junction blockers, 18-alpha-glycyrrhetnic acid-3-hemisuccinate and 18-beta-glycyrrhetnic acid, were applied to the explant cultures. Both blockers produced a rapid and persistent reduction in iodopsin and AANAT mRNA levels. Upon removal of the blockers, the transcript rhythms of both genes reappeared within a 24 hrs. These data suggest that the change in iodopsin mRNA levels was not due to disruption of function or phase of the circadian oscillators driving the transcript rhythms. The blockers may either uncouple the circadian oscillators and the transcription of these two genes or alter stability of both transcripts. Trade Books>Trade Paperback>Science>Biology>Biology, LAP Lambert Academic Publishing Core >1<

2012, ISBN: 3847331701

[EAN: 9783847331704], Nouveau livre, [SC: 15.0], [PU: LAP LAMBERT Academic Publishing], BIOLOGIE RETINA EXPLANT CULTURE CIRCADIAN REGULATION GAP JUNCTIONS GENE EXPRESSION, Autor/Autorin: … mais…

[EAN: 9783847331704], Nouveau livre, [SC: 15.0], [PU: LAP LAMBERT Academic Publishing], BIOLOGIE RETINA EXPLANT CULTURE CIRCADIAN REGULATION GAP JUNCTIONS GENE EXPRESSION, Autor/Autorin: Zhang YanDr. Yan Zhang received a BM and MS degree in Tianjin Medical University, China and a Ph.D. in Neuroscience in University of Florida, USA. He also had a postdoctoral training in Pennington Biomedical Research Center, LSU syst., Books<

2012, ISBN: 9783847331704

LAP LAMBERT Academic Publishing, Taschenbuch, 92 Seiten, Publiziert: 2012-01-06T00:00:01Z, Produktgruppe: Buch, 0.33 kg, Allgemein, Biologie, Biowissenschaften, Naturwissenschaften & Tech… mais…

LAP LAMBERT Academic Publishing, Taschenbuch, 92 Seiten, Publiziert: 2012-01-06T00:00:01Z, Produktgruppe: Buch, 0.33 kg, Allgemein, Biologie, Biowissenschaften, Naturwissenschaften & Technik, Kategorien, Bücher, Taschenbücher, Fremdsprachige Bücher, Englische Bücher, LAP LAMBERT Academic Publishing, 2012<

2012, ISBN: 9783847331704

LAP LAMBERT Academic Publishing, Paperback, 92 Seiten, Publiziert: 2012-01-06T00:00:01Z, Produktgruppe: Book, 0.15 kg, Biological Sciences, Science, Nature & Maths, Subjects, Books, Biolo… mais…

LAP LAMBERT Academic Publishing, Paperback, 92 Seiten, Publiziert: 2012-01-06T00:00:01Z, Produktgruppe: Book, 0.15 kg, Biological Sciences, Science, Nature & Maths, Subjects, Books, Biology, Scientific, Technical & Medical, LAP LAMBERT Academic Publishing, 2012<

ISBN: 3847331701

Role of Gap Junction in Retina Circadian Rhythms ab 48.99 € als Taschenbuch: Gap junction blockade disrupts circadian regulation of gene expression in embryonic retinal explant cultures. … mais…

Role of Gap Junction in Retina Circadian Rhythms ab 48.99 € als Taschenbuch: Gap junction blockade disrupts circadian regulation of gene expression in embryonic retinal explant cultures. Aus dem Bereich: Bücher, Taschenbücher, Naturwissenschaft, LAP LAMBERT Academic Publishing<