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Wnt Signaling - Elizabeth Vincan
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Wnt Signaling - novo libro

ISBN: 9781617378416

Life Sciences; Cell Biology Activation, Calcium, Canonical Wnt/FZD signaling, Degenerative diseases and cancer, Embryogenesis, Non-canonical signaling, Promoter, Protein-protein interacti… mais…

  - Wnt signaling molecules have been shown to control key events in embryogenesis. This book records our progress to date in understanding the intricacies of Wnt signaling. The contributing authors are responsible for shaping the Wnt field. Custos de envio:zzgl. Versandkosten., mais custos de envio
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Wnt Signaling: Volume 1, Pathway Methods and Mammalian Models (Methods in Molecular Biology, Band 468) - Elizabeth Vincan
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Wnt Signaling: Volume 1, Pathway Methods and Mammalian Models (Methods in Molecular Biology, Band 468) - Livro de bolso

ISBN: 1617378410

[SR: 2953201], Taschenbuch, [EAN: 9781617378416], Humana Press, Humana Press, Book, [PU: Humana Press], Humana Press, 56182011, Molekularbiologie, 56458011, Biowissenschaften, 56047011, W… mais…

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Wnt Signaling: Volume 1: Pathway Methods and Mammalian Models (Methods in Molecular Biology, Band 468)
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Wnt Signaling: Volume 1: Pathway Methods and Mammalian Models (Methods in Molecular Biology, Band 468) - Livro de bolso

2011

ISBN: 9781617378416

Humana, Taschenbuch, Auflage: Softcover reprint of hardcover 1st ed. 2008, 352 Seiten, Publiziert: 2011-01-20T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: 13992505, 1.91 kg, Ingenieurw… mais…

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Wnt Signaling: Volume 1: Pathway Methods and Mammalian Models (Methods in Molecular Biology, Band 468)
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Wnt Signaling: Volume 1: Pathway Methods and Mammalian Models (Methods in Molecular Biology, Band 468) - Livro de bolso

2011, ISBN: 9781617378416

Humana, Taschenbuch, Auflage: Softcover reprint of hardcover 1st ed. 2008, 352 Seiten, Publiziert: 2011-01-20T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: 13992505, 1.91 kg, Ingenieurw… mais…

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Wnt Signaling - Elizabeth Vincan
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Elizabeth Vincan:
Wnt Signaling - Livro de bolso

2010, ISBN: 9781617378416

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Volume 1: Pathway Methods and Mammalian Models, Softcover reprint of hardcover 1st ed. 2008, Softcover, Buch, [PU: Humana Press Inc.]

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Wnt Signaling: Volume 1: Pathway Methods and Mammalian Models (Methods in Molecular Biology, Band 468)
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9781617378416


Since their discovery, Wnt signaling molecules have been shown to control key events in embryogenesis, to maintain tissue homeostasis in the adult and, when aberrantly activated, to promote human degenerative diseases and cancer, thus making them a vital area of study. Wnt Signaling: Methods and Protocols examines both biochemical assays and vertebrate and invertebrate model systems to provide a point of reference to current molecular protocols and the diverse model systems employed to study this important signaling pathway. In Volume 1, Pathway Methods and Mammalian Models, assays to measure activation of the diverse Wnt signaling pathways are explored, along with a selection of models and strategies used to study mammalian Wnt/FZD fuction, from protein-protein interaction and simple cell line models to organoid cultures and mouse models. As a volume in the highly successful Methods in Molecular Biology(TM) series, chapters contain readily reproducible laboratory protocols, complete with lists of necessary equipment and reagents and the Notes section, which reveals helpful troubleshooting tips. Comprehensive and cutting-edge, Wnt Signaling: Methods and Protocols collects the expertise and knowledge of many leaders in the field to produce this invaluable two-volume resource.

Dados detalhados do livro - Wnt Signaling: Volume 1: Pathway Methods and Mammalian Models (Methods in Molecular Biology, Band 468)


EAN (ISBN-13): 9781617378416
ISBN (ISBN-10): 1617378410
Livro de capa dura
Livro de bolso
Ano de publicação: 2011
Editor/Editora: Vincan, Elizabeth, Humana
352 Páginas
Língua: eng/Englisch

Livro na base de dados desde 2011-10-18T13:17:21+01:00 (Lisbon)
Página de detalhes modificada pela última vez em 2022-09-25T10:35:16+01:00 (Lisbon)
Número ISBN/EAN: 9781617378416

Número ISBN - Ortografia alternativa:
1-61737-841-0, 978-1-61737-841-6
Ortografia alternativa e termos de pesquisa relacionados:
Título do livro: signaling, wnt pathway, mammalian biology, 468

Dados da editora

Autor: Elizabeth Vincan
Título: Methods in Molecular Biology; Wnt Signaling - Volume 1: Pathway Methods and Mammalian Models
Editora: Humana; Humana Press
336 Páginas
Ano de publicação: 2011-01-20
Totowa; NJ; US
Impresso / Feito em
Peso: 0,867 kg
Língua: Inglês
106,99 € (DE)
109,99 € (AT)
118,00 CHF (CH)
POD
XVI, 336 p. 76 illus., 2 illus. in color.

BC; Cell Biology; Hardcover, Softcover / Biologie/Mikrobiologie; Zellbiologie (Zytologie); Verstehen; Activation; Calcium; Canonical Wnt/FZD signaling; Degenerative diseases and cancer; Embryogenesis; Non-canonical signaling; Promoter; Protein-protein interaction; Tissue homeostasis; Wnt/FZD function; genes; molecular biology; proteins; tissue; transcription; Cell Biology; BB

Part I. Wnt signaling pathway methods A: Canonical Wnt/FZD signaling Chapter 1. The Canonical Wnt/b -Catenin Signaling Pathway. Nick Barker Chapter 2. Isolation and application of bioactive Wnt proteins. Karl Willert Chapter 3: Purification and Wnt inhibitory activity of secreted Frizzled-related proteins. Vladimir Wolf, Yoshimi Endo and Jeffery S Rubin Chapter 4. Measuring GSK3 expression and activity in cells. Adam R Cole and Calum Sutherland Chapter 5.Inhibition of Glycogen Synthase Kinase-3. Andrei V Ougolkov and Daniel D Billadeau Chapter 6. Detection of cytoplasmic and nuclear localization of Adenomatous Polyposis Coli (APC) protein in cells. Mariana Brocardo and Beric R Henderson Chapter 7. Detection of b -catenin localization by immunohistochemistry. Nick Barker and Maaike van den Born Chapter 8. Assaying b -catenin/TCF transcription with b -catenin/TCF transcriptional-based reporter constructs. Travis L Biechele and Randall T Moon Chapter 9. Native promoter reporters validate transcriptional targets. Otto Schmalhofer, Simone Spaderna and Thomas Brabletz B: Non-canonical Signaling Chapter 10. b -Catenin-independent Wnt pathways: signals, core protein and effectors. Richard G James, William H Conrad and Randall T Moon Chapter 11. Image Analysis of Calcium Release Dynamics. Christina M Freisinger, Douglas W Houston and Diane Slusarski Chapter 12. Detecting PKC phosphorylation as part of the Wnt/calcium pathway in cutaneous melanoma. Samudra K Dissanayake and Ashani Weeraratna Chapter 13. Measuring CamK II activity in Xenopus embryos as a read-out for non-canonical Wnt signaling. Michael Kuhl and Petra Pandur Chapter 14. Analysis of Wnt7a-stimulated JNK activity and cJUN Phosphorylation in Non-Small Cell Lung Cancer Cells. Lynn E Heasley and Robert A Winn Chapter 15. ROCK enzymatic assay. John D Doran and Marc D Jacobs Chapter 16. Detection of Planar polarity proteins in mammalian cochlea. Mireille Montcouquiol and Nathalie Sans Part II. Mammalian Model systems for Wnt/FZD function Chapter 17. Proteomic analyses of protein complexes in the Wnt pathway. Stephane Angers Chapter 18. In situ hybridization to evaluate the expression of Wnt and Frizzled genes in mammalian tissues. Kestutis Planutis, Marina Planutiene and Randall F Holcombe Chapter 19. Assaying Wnt5a-mediated invasion in melanoma cells. Michael P. O’Connell, Amanda D. French, Poloko D. Leotlela and Ashani T. Weeraratna Chapter 20. Co-culture methodologies for the study of Wnt signals. Kestutis Planutis, Marina Planutiene and Randall F Holcombe Chapter 21. Analysis of Wnt/FZD-mediated signaling in a cell line model of colorectal cancer morphogenesis. Elizabeth Vincan, Robert H Whitehead and Maree C Faux Chapter 22. Analyzing tissue and gene function in intestinal organ culture. Helen E Abud. Heather M Young and Donald F Newgreen Chapter 23. The Genetics of Wnt Signaling During Early Mammalian Development. Terry Yamaguchi Chapter 24. Tissue-specific Transgenic, Conditional Knock-out and Knock-in Mice of Genes in the Canonical Wnt signaling Pathway. Koji Aoki and Makoto M Taketo

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