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Protein-Protein Interactions as New Drug Targets - John Scott
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Protein-Protein Interactions as New Drug Targets - Livro de bolso

2010, ISBN: 3642091946

[EAN: 9783642091940], New book, [SC: 9.42], [PU: Springer Berlin Heidelberg Okt 2010], COMPARTIMENTALISATION; PEPTIDEDISRUPTORS; PROTEIN-PROTEININTERACTIONS; SCAFFOLDINGPROTEINS; SMALLMOL… mais…

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Protein-Protein Interactions as New Drug Targets (Handbook of Experimental Pharmacology, 186, Band 186)
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Protein-Protein Interactions as New Drug Targets (Handbook of Experimental Pharmacology, 186, Band 186) - Livro de bolso

2010, ISBN: 9783642091940

Springer, Taschenbuch, Auflage: Softcover reprint of hardcover 1st ed. 2008, 527 Seiten, Publiziert: 2010-10-19T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: 53 black & white illustrati… mais…

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Protein-Protein Interactions as New Drug Targets: 186 (Handbook of Experimental Pharmacology, 186)
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Protein-Protein Interactions as New Drug Targets: 186 (Handbook of Experimental Pharmacology, 186) - Livro de bolso

2010

ISBN: 9783642091940

Editor: Klussmann, Enno, Editor: Scott, John, Springer, Paperback, Auflage: Softcover reprint of hardcover 1st ed. 2008, 527 Seiten, Publiziert: 2010-10-19T00:00:01Z, Produktgruppe: Book,… mais…

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Protein-Protein Interactions as New Drug Targets - Scott, John (Herausgeber); Klussmann, Enno (Herausgeber)
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Scott, John (Herausgeber); Klussmann, Enno (Herausgeber):
Protein-Protein Interactions as New Drug Targets - Livro de bolso

2010, ISBN: 3642091946

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Softcover reprint of hardcover 1st ed. 2008 Kartoniert / Broschiert Pharmakologie, Medizinische Chemie, Pharmazeutische Chemie, Zellbiologie (Zytologie), Compartimentalisation; PeptideD… mais…

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Protein-Protein Interactions as New Drug Targets - Scott John
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Scott John:
Protein-Protein Interactions as New Drug Targets - livro usado

ISBN: 9783642091940

Livre, [PU: Springer, Berlin/Heidelberg/New York, NY]

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Protein-Protein Interactions as New Drug Targets (Handbook of Experimental Pharmacology, 186, Band 186)
Autor:
Título:
Número ISBN:

9783642091940


Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions. This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted.

Dados detalhados do livro - Protein-Protein Interactions as New Drug Targets (Handbook of Experimental Pharmacology, 186, Band 186)


EAN (ISBN-13): 9783642091940
ISBN (ISBN-10): 3642091946
Livro de capa dura
Livro de bolso
Ano de publicação: 2010
Editor/Editora: Klussmann, Enno, Scott, John, Springer
528 Páginas
Peso: 0,789 kg
Língua: eng/Englisch

Livro na base de dados desde 2011-02-18T13:56:54+00:00 (Lisbon)
Página de detalhes modificada pela última vez em 2023-06-17T15:09:52+01:00 (Lisbon)
Número ISBN/EAN: 9783642091940

Número ISBN - Ortografia alternativa:
3-642-09194-6, 978-3-642-09194-0
Ortografia alternativa e termos de pesquisa relacionados:
Autor do livro: klußmann, enno von, klussmann, john scott, klüssmann
Título do livro: protein protein interactions, protein protein interaction

Dados da editora

Autor: Enno Klussmann; John Scott
Título: Handbook of Experimental Pharmacology; Protein-Protein Interactions as New Drug Targets
Editora: Springer; Springer Berlin
512 Páginas
Ano de publicação: 2010-10-19
Berlin; Heidelberg; DE
Impresso / Feito em
Língua: Inglês
320,99 € (DE)
329,99 € (AT)
354,00 CHF (CH)
POD
XV, 512 p.

BC; Hardcover, Softcover / Medizin/Pharmazie; Pharmakologie; Verstehen; Compartimentalisation; Peptide Disruptors; Protein-Protein Interactions; Scaffolding Proteins; Small Molecules; proteins; Pharmacology; Cell Biology; Medical Biochemistry; Biomedical Research; Zellbiologie (Zytologie); Medizinische Chemie, Pharmazeutische Chemie; Medizinische Forschung; BB

Organization of Scaffolds.- A-Kinase Anchoring Proteins as the Basis for cAMP Signaling.- Arrestins as Multi-Functional Signaling Adaptors.- Role of Ena/VASP Proteins in Homeostasis and Disease.- Scaffold/Matrix Attachment Regions (S/MARs): Relevance for Disease and Therapy.- Clathrin/AP-2-Dependent Endocytosis: A Novel Playground for the Pharmacological Toolbox?.- Scaffolding Proteins and Cellular Signalling.- PDE4 Associates with Different Scaffolding Proteins: Modulating Interactions as Treatment for Certain Diseases.- G-Protein-Coupled Receptor-Signaling Components in Membrane Raft and Caveolae Microdomains.- Protein Scaffolds, Lipid Domains and Substrate Recognition in Protein Kinase C Function: Implications for Rational Drug Design.- Compartmentalised MAPK Pathways.- Dynamic Protein Complexes Regulate NF-?B Signaling.- An Oncogenic Hub: ?-Catenin as a Molecular Target for Cancer Therapeutics.- A Toolkit for Real-Time Detection of cAMP: Insights into Compartmentalized Signaling.- Cell Type-Specific Anchoring.- Scaffolding Proteins in Cardiac Myocytes.- Molecular Architecture of Signal Complexes Regulating Immune Cell Function.- Scaffolding Proteins at the Postsynaptic Density: Shank as the Architectural Framework.- Interference with Protein-Protein Interaction Sites as a New Pharmacological Concept.- Domains Mediate Protein-Protein Interactions and Nucleate Protein Assemblies.- Proline-Rich Sequence Recognition Domains (PRD): Ligands, Function and Inhibition.- Chemical Inhibition Through Conformational Stabilization of Rho GTPase Effectors.- Pharmacological Interference with Protein-Protein Interactions Mediated by Coiled-Coil Motifs.- Direct AKAP-Mediated Protein-Protein Interactions as Potential Drug Targets.

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