ISBN: 9783659281051

Cervical cancer is one of the most frequent diseases in women,it is comprises approximately 12% of all cancer in women worldwide and the second most common type, after breast cancer, with… mais…

Cervical cancer is one of the most frequent diseases in women,it is comprises approximately 12% of all cancer in women worldwide and the second most common type, after breast cancer, with about 200,000 deaths annually and 500,000 new cases per annum. Persistent infection with one or more carcinogenic types of human papillomavirus (HPV) is an important etiologic factor in the development of cervical intraepithelial neoplasia and the progression to cervical cancer. HPV DNA has been detected in up to 99.7% of invasive cervical cancers worldwide.The carcinogenic effect of the high-risk HPVs, as defined by their documented association with invasive carcinomas, is thought to be mediated by two viral oncoprotein, E6 and E7, through their action of inactivating the function of two important cellular tumor suppressor, p53 and pRb. It has been demonstrated that the E6 oncoprotein interacts with p53 to promote its degradation, whereas the E7 oncoprotein form complex with Rb, leading to its functional inactivation as well as accelerated degradation. These synergistic effects result in a deregulated cell cycle control and are thus believed to be critically important in HPV-induced carcinogene Trade Books>Trade Paperback>Science>Biology>Biology, LAP Lambert Academic Publishing Core >1<

ISBN: 9783659281051

Paperback, [PU: LAP Lambert Academic Publishing], Cervical cancer is one of the most frequent diseases in women, it is comprises approximately 12% of all cancer in women worldwide and the… mais…

Paperback, [PU: LAP Lambert Academic Publishing], Cervical cancer is one of the most frequent diseases in women, it is comprises approximately 12% of all cancer in women worldwide and the second most common type, after breast cancer, with about 200,000 deaths annually and 500,000 new cases per annum. Persistent infection with one or more carcinogenic types of human papillomavirus (HPV) is an important etiologic factor in the development of cervical intraepithelial neoplasia and the progression to cervical cancer. HPV DNA has been detected in up to 99.7% of invasive cervical cancers worldwide.The carcinogenic effect of the "high-risk" HPVs, as defined by their documented association with invasive carcinomas, is thought to be mediated by two viral oncoprotein, E6 and E7, through their action of inactivating the function of two important cellular tumor suppressor, p53 and pRb. It has been demonstrated that the E6 oncoprotein interacts with p53 to promote its degradation, whereas the E7 oncoprotein form complex with Rb, leading to its functional inactivation as well as accelerated degradation. These synergistic effects result in a deregulated cell cycle control and are thus believed to be critically important in HPV-induced carcinogene, Microbiology (non-medical)<

2013, ISBN: 3659281050

[EAN: 9783659281051], Neubuch, [PU: LAP LAMBERT Academic Publishing], BIOLOGIE MIKROBIOLOGIE CERVICAL CARCINOMA HUMAN PAPILLOMAVIRUS (HPV), Dieser Artikel ist ein Print on Demand Artikel … mais…

[EAN: 9783659281051], Neubuch, [PU: LAP LAMBERT Academic Publishing], BIOLOGIE MIKROBIOLOGIE CERVICAL CARCINOMA HUMAN PAPILLOMAVIRUS (HPV), Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Al-Shuwaikh ArwaDr.Arwa M. Al-Shuwaikh has obtained her PhD degree in 2013 from Al-Nahrain College of Medicine, Baghdad, Iraq. She has held faculty positions in Microbiology Department at Al-Nahrain College of Medicine. She has worke., Books<

2013, ISBN: 9783659281051

Livro de bolso

[ED: Kartoniert / Broschiert], [PU: LAP LAMBERT Academic Publishing], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Al-Sh… mais…

[ED: Kartoniert / Broschiert], [PU: LAP LAMBERT Academic Publishing], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Al-Shuwaikh ArwaDr.Arwa M. Al-Shuwaikh has obtained her PhD degree in 2013 from Al-Nahrain College of Medicine, Baghdad, Iraq. She has held facul, DE, Neuware, gewerbliches Angebot, Taschenbuch, 132, [GW: 215g], 1. Auflage, Banküberweisung, PayPal<

ISBN: 9783659281051

Edição encadernada

*High-Risk Human Papillomavirus and Cervical Carcinoma* - A Study on Human Papillomavirus: High-Risk E6 p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis / Taschen… mais…

*High-Risk Human Papillomavirus and Cervical Carcinoma* - A Study on Human Papillomavirus: High-Risk E6 p53 and p16 Proteins Expression and Their Role in Cervical Carcinogenesis / Taschenbuch für 55.99 € / Aus dem Bereich: Bücher, Taschenbücher, Naturwissenschaft Medien > Bücher nein Taschenbuch Hardcover;Naturwissenschaften, Medizin, Informatik, Technik;Mikrobiologie, LAP LAMBERT Academic Publishing<